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2378837-67-1

2378837-67-1 Structure

2378837-67-1 Structure
IdentificationBack Directory
[Name]

4,13,16,19-Tetraoxa-7,10-diazaheneicosanamide, N-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethyl]-6,6-bis[[3-[[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethyl]amino]-3-oxopropoxy]methyl]-21-[(2,4-dinitrophenyl)amino]-8,11-dioxo-
[CAS]

2378837-67-1
[Synonyms]

4,13,16,19-Tetraoxa-7,10-diazaheneicosanamide, N-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethyl]-6,6-bis[[3-[[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethyl]amino]-3-oxopropoxy]methyl]-21-[(2,4-dinitrophenyl)amino]-8,11-dioxo-
[Molecular Formula]

C71H121N11O39
[MOL File]

2378837-67-1.mol
[Molecular Weight]

1752.77
Chemical PropertiesBack Directory
[Boiling point ]

1726.0±65.0 °C(Predicted)
[density ]

1.42±0.1 g/cm3(Predicted)
[pka]

12.49±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

D-MoDE-A (1) is a bifunctional small molecule that mediates the degradation of extracellular proteins through the asialoglycoprotein receptor (ASGPR).
[References]

[1] Caianiello DF, et al. Bifunctional small molecules that mediate the degradation of extracellular proteins. Nat Chem Biol. 2021 Sep;17(9):947-953. DOI:10.1038/s41589-021-00851-1
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