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2388520-23-6

2388520-23-6 Structure

2388520-23-6 Structure
IdentificationBack Directory
[Name]

21-[4-(4-Amino-2-butyl-3H-imidazo[4,5-c]quinolin-8-yl)-1-piperazinyl]-4,7,10,13,16,19-hexaoxaheneicosanoic acid
[CAS]

2388520-23-6
[Synonyms]

TLR7/8 agonist 4 hydroxy-PEG6-acid
21-[4-(4-Amino-2-butyl-3H-imidazo[4,5-c]quinolin-8-yl)-1-piperazinyl]-4,7,10,13,16,19-hexaoxaheneicosanoic acid
[Molecular Formula]

C33H52N6O8
[MOL File]

2388520-23-6.mol
[Molecular Weight]

660.8
Chemical PropertiesBack Directory
[Boiling point ]

858.7±65.0 °C(Predicted)
[density ]

1.226±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[pka]

4.28±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

TLR7/8 agonist 4 hydroxy-PEG6-acid is a drug-linker conjugates for ADC. TLR7/8 agonist 4 hydroxy-PEG6-acid consists of TLR7/8 agonist 4 (HY-139017) and a non-cleavable linker Hydroxy-PEG6-acid (HY-133050), and can be used for synthesis of ADCs[1].
[References]

[1] Shelley Erin ACKERMAN, et al. Macromolecule-supported tlr agonists. Patent. WO2020190762A1.
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