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2389062-09-1

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2389062-09-1 Structure

2389062-09-1 Structure
IdentificationBack Directory
[Name]

NED-3238
[CAS]

2389062-09-1
[Synonyms]

NED-3238
NED3238,NED 3238
[Molecular Formula]

C17H28BN3O4
[MDL Number]

MFCD32201107
[MOL File]

2389062-09-1.mol
[Molecular Weight]

349.24
Chemical PropertiesBack Directory
[Boiling point ]

598.5±60.0 °C(Predicted)
[density ]

1.213±0.06 g/cm3(Predicted)
[pka]

10.32±0.43(Predicted)
Hazard InformationBack Directory
[Uses]

NED-3238 is a highly potent arginase I and II inhibitor with IC50 values of 1.3 nM and 8.1 nM, respectively[1].
[References]

[1] Van Zandt MC, et al. Discovery of N-Substituted 3-Amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase I and II. J Med Chem. 2019 Aug 23. DOI:10.1021/acs.jmedchem.9b00931
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