| Identification | Back Directory | [Name]
2(1H)-Pyridinone, 3-(2-bromophenyl)-5-(phenylamino)- | [CAS]
2396754-57-5 | [Synonyms]
p38-α MAPK-IN-4
2(1H)-Pyridinone, 3-(2-bromophenyl)-5-(phenylamino)- | [Molecular Formula]
C17H13BrN2O | [MOL File]
2396754-57-5.mol | [Molecular Weight]
341.2 |
| Hazard Information | Back Directory | [Uses]
p38-α MAPK-IN-4 (Compound 69) is a selective p38α MAPK inhibitor with an IC50 of 1.5 μM. p38-α MAPK-IN-4 rapidly and strongly prevents the development of mechanical allodynia (MA) in vivo[1]. | [IC 50]
p38α MAPK: 1.5 μM (IC50) | [References]
[1] Visseq A, et al. Pyridin-2(1H)one derivatives: A possible new class of therapeutics for mechanical allodynia. Eur J Med Chem. 2020 Feb 1;187:111917. DOI:10.1016/j.ejmech.2019.111917 |
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