| Identification | More | [Name]
1,2-Dichloro-3-iodobenzene | [CAS]
2401-21-0 | [Synonyms]
1,2-DICHLORO-3-IODOBENZENE
2,3-Dichloro-1-iodobenzene
2,3-DICHLOROIODOBENZENE
1-Iodo-2,3-dichlorobenzene
1 2-DICHLORO-3-IODOBENZENE 97%
4-IodotolueneDichloride(Tol-Icl2)
2,3-Dichloroiodobenzene, 98+%
1,2-Dichloro-3-iodobenzene,98+%
1,3-Dichloro-5-iodo-2-methylbenzene
2,3-DICHOROIODOBENZENE
BENZENE,1,2-DICHLORO-3-IODO
2,3-Dichlorophenyl iodide
3-Iodo-o-dichlorobenzene | [EINECS(EC#)]
219-276-0 | [Molecular Formula]
C6H3Cl2I | [MDL Number]
MFCD00001034 | [Molecular Weight]
272.9 | [MOL File]
2401-21-0.mol |
| Chemical Properties | Back Directory | [Appearance]
white crystalline mass | [Melting point ]
35-36 °C(lit.) | [Boiling point ]
123-126 °C20 mm Hg(lit.) | [density ]
1.9882 (estimate) | [Fp ]
>230 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
very faint turbidity in Methanol | [form ]
Crystalline Mass | [color ]
White | [Sensitive ]
Light Sensitive | [BRN ]
2247168 | [CAS DataBase Reference]
2401-21-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29039990 |
| Hazard Information | Back Directory | [Chemical Properties]
white crystalline mass | [Uses]
1,2-Dichloro-3-iodobenzene is a Iodobenzenes chemical, which has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. | [Synthesis]
The general procedure for synthesizing 1,2-dichloro-3-iodobenzene from iodobenzene is as follows: in Example 6, the preparation of dichloroiodobenzene, chlorine gas was passed in a bubbling manner into a solution of iodobenzene (20.4 g; 0.1 mol) dissolved in chloroform (100 ml), while controlling the temperature of the reaction mixture to be maintained at -5 °C. After about 10 minutes, a yellow solid precipitate appeared in the reaction mixture, which was separated by filtration. Subsequently, chlorine gas was continued to be passed into the filtrate until no more yellow solid was produced. All obtained solid portions were combined and dried in air to give 25.9 g (94.2% yield) of the target product 1,2-dichloro-3-iodobenzene. | [References]
[1] Dalton Transactions, 2014, vol. 44, # 1, p. 119 - 129
[2] Patent: US4203918, 1980, A
[3] Patent: US4358607, 1982, A |
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