Identification | More | [Name]
2-Amino-3-benzyloxypyridine | [CAS]
24016-03-3 | [Synonyms]
2-AMINO-3-BENZYLOXYPYRIDINE 3-Benzyloxy-2-pyridylamine 3-(BENZYLOXY)PYRIDIN-2-AMINE TIMTEC-BB SBB000394 3-Benzyloxy-2-aminopyridine 3-Benzyloxy-pyridin-2-ylamine 4-(Benzyloxy)-2-pyridinamine Pyridine, 2-amino-3-(benzyloxy)- 2-Amino-3-benzyloxypyridine, 98+% 2-Amino-3-benzyloxypyridine, 98.50% 2-Pyridinamine, 3-(phenylmethoxy)- 3-(Phenylmethoxy)pyridin-2-amine 3-(Benzyloxy)pyridine-2-amine 3-(Phenylmethoxy)-2-pyridinamine | [EINECS(EC#)]
245-983-9 | [Molecular Formula]
C12H12N2O | [MDL Number]
MFCD00006316 | [Molecular Weight]
200.24 | [MOL File]
24016-03-3.mol |
Chemical Properties | Back Directory | [Appearance]
Brown crystalline powder | [Melting point ]
92-94 °C (lit.) | [Boiling point ]
337.96°C (rough estimate) | [density ]
1.1131 (rough estimate) | [refractive index ]
1.6660 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Crystalline Powder | [pka]
8.40±0.10(Predicted) | [color ]
Green to brown | [BRN ]
392674 | [InChI]
InChI=1S/C12H12N2O/c13-12-11(7-4-8-14-12)15-9-10-5-2-1-3-6-10/h1-8H,9H2,(H2,13,14) | [InChIKey]
NMCBWICNRJLKKM-UHFFFAOYSA-N | [SMILES]
C1(N)=NC=CC=C1OCC1=CC=CC=C1 | [CAS DataBase Reference]
24016-03-3(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Pyridinamine, 3-(phenylmethoxy)-(24016-03-3) |
Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S37/39:Wear suitable gloves and eye/face protection . S24/25:Avoid contact with skin and eyes . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S36:Wear suitable protective clothing . | [RIDADR ]
UN2811 | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29333990 |
Hazard Information | Back Directory | [Chemical Properties]
Brown crystalline powder | [Uses]
2-Amino-3-benzyloxypyridine is used in preparation of pyridinyl/pyridazinyloxymethyl substituted Raf kinase inhibitors. | [General Description]
2-Amino-3-benzyloxypyridine on condensation with diethyl ethoxymethylene malonate affords 9-benzyloxy-3-ethoxycarbonylpyrido[1,2-a]pyrimidin-4-one. | [Biochem/physiol Actions]
2-Amino-3-benzyloxypyridine is an inhibitor of mitogen-activated protein kinase p38α activity. |
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