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240405-20-3

240405-20-3 Structure

240405-20-3 Structure
IdentificationBack Directory
[Name]

2,3-DINOR-11BETA-PROSTAGLANDIN F2ALPHA
[CAS]

240405-20-3
[Synonyms]

Prostaglandin Impurity 1
ProstaglandinImpurity1-d4
IDKLJIUIJUVJNR-KSJYGFEGSA-N
2,3-dinor-11β-Prostaglandin F2α
2,3-dinor-11β-Prostaglandin F2α
2,3-DINOR-11BETA-PROSTAGLANDIN F2ALPHA
2,3-dinor-11β-Prostaglandin F2α Lipid Maps MS Standard
9ALPHA,11BETA,15S-TRIHYDROXY-2,3-DINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
2,3 dinor 11β Prostaglandin F2α,2,3dinor11βProstaglandin F2α,2,3-dinor-11β-Prostaglandin F-2α
3-Pentenoic acid, 5-[(1R,2R,3S,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]cyclopentyl]-, (3Z)-
[Molecular Formula]

C18H30O5
[MDL Number]

MFCD02259339
[MOL File]

240405-20-3.mol
[Molecular Weight]

326.43
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 100 mg/ml; DMSO: 100 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): 10 mg/ml
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H225-H319-H350
[Precautionary statements ]

P201-P202-P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P308+P313-P337+P313-P370+P378-P403+P235-P405-P501
Hazard InformationBack Directory
[Description]

2,3-dinor-11β-Prostaglandin F (2,3-dinor-11β-PGF) is a metabolite of PGD2 . Urinary excretion of 2,3-dinor-11β-PGF is increased in patients with mast cell activation disease (MCAD) and has been used as a marker of increased PGD2 levels. 2,3-dinor-11 β-PGF levels are also increased in the urine of patients with asthma and are positively correlated with impaired lung function.
[Uses]

2,3-Dinor-11beta-prostaglandin F2alpha (2,3-Dinor-11β-PGF2α) is a metabolite of PGD2. Urinary excretion of 2,3-Dinor-11beta-prostaglandin F2alpha is increased in patients with mast cell activation disease (MCAD) and has been used as a marker of increased PGD2 levels. 2,3-Dinor-11beta-prostaglandin F2alpha levels are also increased in the urine of patients with asthma and are positively correlated with impaired lung function.
[Definition]

ChEBI: 2,3-Dinor-11b-PGF2alpha is a prostanoid.
[References]

[1] Liston, et al. J. Biol. Chem. 260(24), 13172-13180 (1985).
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