| Identification | Back Directory | [Name]
prostaglandin D2 methyl ester | [CAS]
49852-81-5 | [Synonyms]
WNBMQMMGBBWUOZ-BYNKDMOPSA-N
prostaglandin D2 methyl ester
Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, methyl ester, (5Z,9α,13E,15S)- | [Molecular Formula]
C21H34O5 | [MDL Number]
MFCD00133787 | [MOL File]
49852-81-5.mol | [Molecular Weight]
366.49 |
| Chemical Properties | Back Directory | [Boiling point ]
510.0±50.0 °C(Predicted) | [density ]
1.103±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml | [form ]
Liquid | [pka]
13.85±0.60(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
Prostaglandin D2 methyl ester is a prodrug form of Prostaglandin D2. Prostaglandin D2 methyl ester binds to the human and mouse PGD2 receptors (DP and CRTH2) with Ki values of 160 nM, 175 nM, 460 nM, and 270 nM for mCRTH2, mDP, hCRTH2, and hDP, respectively[1]. | [Definition]
ChEBI: Prostaglandin D2 methyl ester is a prostanoid. | [References]
[1] Hiroyuki Hirai, et al. Gene structure and functional properties of mouse CRTH2, a prostaglandin D2 receptor. Biochem Biophys Res Commun. 2003 Aug 8;307(4):797-802. DOI:10.1016/s0006-291x(03)01266-x |
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