| Identification | Back Directory | [Name]
3-Pyridinecarboxamide, N-[3'-[[4-(2-aminoethyl)-1-piperazinyl]methyl]-4-(4-methyl-1-piperazinyl)[1,1'-biphenyl]-3-yl]-1,6-dihydro-6-oxo-4-(trifluoromethyl)- | [CAS]
2407457-55-8 | [Synonyms]
OICR-9429-N-C2-NH2
3-Pyridinecarboxamide, N-[3'-[[4-(2-aminoethyl)-1-piperazinyl]methyl]-4-(4-methyl-1-piperazinyl)[1,1'-biphenyl]-3-yl]-1,6-dihydro-6-oxo-4-(trifluoromethyl)- | [Molecular Formula]
C31H38F3N7O2 | [MOL File]
2407457-55-8.mol | [Molecular Weight]
597.67 |
| Hazard Information | Back Directory | [Uses]
OICR-9429-N-C2-NH2 is a ligand for Wd40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1, intermediate 2. OICR-9429-N-C2-NH2 can be used in the synthesis of PROTACs[1]. | [References]
[1] Jin J, et, al. Wd40 repeat domain protein 5 (wdr5) degradation / disruption compounds and methods of use. WO2019246570A1.
[2] Chung CW, et, al. Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. ACS Chem Biol. 2020 Sep 18;15(9):2316-2323. DOI:10.1021/acschembio.0c00266 |
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