| Chemical Properties | Back Directory | [Boiling point ]
714.149±60.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.034±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [solubility ]
Ethanol: 25 mg/ml | [form ]
Liquid | [pka]
10.044±0.25(predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
LNP Lipid-8 (11-A-M) is an ionizable lipid, which can be used for lipid nanoparticles (LNP) to deliver siRNA to T cells without targeting to ligands. LNP LIPs-8 loaded with GFP siRNA (siGFP), and significantly causes GFP gene silencing in mice model[1]. | [References]
[1] Lokugamage MP, et al. Constrained Nanoparticles Deliver siRNA and sgRNA to T Cells In Vivo without Targeting Ligands. Adv Mater. 2019 Oct;31(41):e1902251. DOI:10.1002/adma.201902251 |
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