| Identification | Back Directory | [Name]
1H-Imidazole-2-carboxylic acid, 1-[3-(2-ethyl-1-piperidinyl)propyl]-5,5-di(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester | [CAS]
2412492-09-0 | [Synonyms]
A18-Iso5-2DC18
1H-Imidazole-2-carboxylic acid, 1-[3-(2-ethyl-1-piperidinyl)propyl]-5,5-di(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester | [Molecular Formula]
C50H93N3O2 | [MOL File]
2412492-09-0.mol | [Molecular Weight]
768.29 |
| Chemical Properties | Back Directory | [Boiling point ]
771.3±60.0 °C(Predicted) | [density ]
0.94±0.1 g/cm3(Predicted) | [form ]
Viscous Liquid | [pka]
9.80±0.10(Predicted) | [color ]
Yellow to brown |
| Hazard Information | Back Directory | [Uses]
A18-Iso5-2DC18 (Compound A18) is a cyclic lipidoid. A18-Iso5-2DC18 partially activates STING. A18-Iso5-2DC18 promotes mRNA protein expression and induces a strong immune response. A18-Iso5-2DC18 can be used in melanoma research[1]. | [in vivo]
LNPs containing A18-Iso5-2DC18 significantly inhibit tumor growth and prolong the survival of mice in the B16F10-OVA mouse melanoma model[1].
| [References]
[1] Miao L, et, al. Ionizable lipidoids and their uses. WO2020047399A1. |
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DC Chemicals
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021-58447131 13564518121 |
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www.chemicalbook.com/showsupplierproductslist927327/0_en.htm |
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