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2414393-22-7

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2414393-22-7 Structure

2414393-22-7 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2414393-22-7
[Synonyms]

MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan
[Molecular Formula]

C55H60FN9O13
[MOL File]

2414393-22-7.mol
[Molecular Weight]

1074.12
Chemical PropertiesBack Directory
[density ]

1.48±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

11.18±0.40(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is a agent-linker conjugate for ADC, contains the ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan synthesized ADC can be used in study of cancer[1].
[IC 50]

Camptothecins
[References]

[1] HUA Haiqing, et al. Antibody-drug conjugate and medical use thereof. Patent WO2021190564A1.
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