| Identification | Back Directory | [Name]
Imidazo[1,2-a]pyridine-3-acetamide, N-(1,1-dioxidobenzo[b]thien-6-yl)-7-methoxy-2-[4-(trifluoromethyl)phenyl]- | [CAS]
2416196-47-7 | [Synonyms]
Imidazo[1,2-a]pyridine-3-acetamide, N-(1,1-dioxidobenzo[b]thien-6-yl)-7-methoxy-2-[4-(trifluoromethyl)phenyl]- | [Molecular Formula]
C25H18F3N3O4S | [MOL File]
2416196-47-7.mol | [Molecular Weight]
513.49 |
| Hazard Information | Back Directory | [Uses]
WZ-2-033 is a potent STAT3 inhibitor. WZ-2-033 inhibits MDA-MB-231, HCC70, and MDA-MB231-4175 cells proliferation, colony survival, migration, and invasion with IC50s of 0.7, 1.3, and 1.3 μM, respectively[1]. | [References]
[1] Zhong Y, et al. The novel STAT3 inhibitor WZ-2-033 causes regression of human triple-negative breast cancer and gastric cancer xenografts. Acta Pharmacol Sin. 2022 Apr;43(4):1013-1023. DOI:10.1038/s41401-021-00718-0 |
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