| Chemical Properties | Back Directory | [Boiling point ]
591.9±50.0 °C(Predicted) | [density ]
1.288±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
12.27±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
VT-105 is a potent and selective TEAD Auto-palmitoylation inhibitor that Inhibits Proliferation and Tumor Growth of NF2-deficient Mesothelioma. VT105 is a more soluble analog of VT104. | [Uses]
VT-105 is a potent and selective TEAD autopalmitoylation inhibitor that inhibits proliferation and tumor growth in NF2-deficient mesothelioma. | [References]
[1] Tang TT, et al. Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. Mol Cancer Ther. 2021 Jun;20(6):986-998. DOI:10.1158/1535-7163.MCT-20-0717 |
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