| Identification | Back Directory | [Name]
Benzenesulfonyl fluoride, 3-[[[5-chloro-4-[[1,2-dihydro-8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-6-quinolinyl]amino]-2-pyrimidinyl]amino]methyl]- | [CAS]
2418022-85-0 | [Synonyms]
Benzenesulfonyl fluoride, 3-[[[5-chloro-4-[[1,2-dihydro-8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-6-quinolinyl]amino]-2-pyrimidinyl]amino]methyl]- | [Molecular Formula]
C25H24ClFN6O6S | [MOL File]
2418022-85-0.mol | [Molecular Weight]
591.01 |
| Hazard Information | Back Directory | [Description]
TMX-2164 is a BCL6 inhibitor. | [Uses]
TMX-2164 is a potent, irreversible B-cell lymphoma 6 (BCL6) inhibitor with an IC50 value of 152 nM. TMX-2164 displays sustained target engagement and antiproliferative activity in cells[1]. | [References]
[1] Teng M, et, al. Rationally Designed Covalent BCL6 Inhibitor That Targets a Tyrosine Residue in the Homodimer Interface. ACS Med Chem Lett. 2020 Apr 3;11(6):1269-1273. DOI:10.1021/acsmedchemlett.0c00111 |
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