| Identification | Back Directory | [Name]
1H-Pyrazole, 3-[(1E)-2-(2,6-difluorophenyl)diazenyl]-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]- | [CAS]
2418049-54-2 | [Synonyms]
piCRAC-1
1H-Pyrazole, 3-[(1E)-2-(2,6-difluorophenyl)diazenyl]-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]- | [Molecular Formula]
C17H10F6N4 | [MOL File]
2418049-54-2.mol | [Molecular Weight]
384.28 |
| Chemical Properties | Back Directory | [Boiling point ]
443.6±45.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 100 mg/mL (260.23 mM) | [form ]
Solid | [pka]
-1.74±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
piCRAC-1 is a potent, photoinducible Ca2+ release-activated Ca2+ (CRAC) channel inhibitor. piCRAC-1 alleviates thrombocytopenia and hemorrhage[1]. | [storage]
Store at -20°C | [References]
[1] Yang X, et al. Optical Control of CRAC Channels Using Photoswitchable Azopyrazoles. J Am Chem Soc. 2020 May 20;142(20):9460-9470. |
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