| Identification | Back Directory | [Name]
Butanamide, N-[(3,5-difluorophenyl)methyl]-N-hydroxy-2,2-dimethyl- | [CAS]
2428422-17-5 | [Synonyms]
RIP1 kinase inhibitor 5
Butanamide, N-[(3,5-difluorophenyl)methyl]-N-hydroxy-2,2-dimethyl- | [Molecular Formula]
C13H17F2NO2 | [MOL File]
2428422-17-5.mol | [Molecular Weight]
257.28 |
| Hazard Information | Back Directory | [Uses]
RIP1 kinase inhibitor 5 (example 1) is a potent inhibitor of RIP1, which is used as a checkpoint kinase to control tumor immunity[1]. RIP1 kinase inhibitor 5 is similar with SIR1-365 (compound 13), which inhibits necrosis and iron death activity[2]. | [References]
[1] Su Yaning, et al. Preparation of cyrstalline forms of RIP1 inhibitor. World Intellectual Property Organization, WO2023066368 A1. 2023-04-27.
[2] Su Yaning, et al. Preparation of substituted amides as RIP1 inhibitors. World Intellectual Property Organization, WO2020103859 A1. 2020-05-28. |
|
|