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2428640-18-8

2428640-18-8 Structure

2428640-18-8 Structure
IdentificationBack Directory
[Name]

1H-Benzimidazole-6-carboxylic acid, 2-[[6-[(4-cyano-2-fluorophenyl)methoxy]-3',6'-dihydro[2,4'-bipyridin]-1'(2'H)-yl]methyl]-1-[(2S)-2-oxetanylmethyl]-
[CAS]

2428640-18-8
[Synonyms]

GLP-1R agonist 3
1H-Benzimidazole-6-carboxylic acid, 2-[[6-[(4-cyano-2-fluorophenyl)methoxy]-3',6'-dihydro[2,4'-bipyridin]-1'(2'H)-yl]methyl]-1-[(2S)-2-oxetanylmethyl]-
[Molecular Formula]

C31H28FN5O4
[MOL File]

2428640-18-8.mol
[Molecular Weight]

553.58
Chemical PropertiesBack Directory
[Boiling point ]

803.9±65.0 °C(Predicted)
[density ]

1.39±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

3.38±0.30(Predicted)
[color ]

White to light yellow
[InChIKey]

HLOTYODPTNOHMJ-DEOSSOPVSA-N
[SMILES]

C1(CN2CCC(C3=NC(OCC4=CC=C(C#N)C=C4F)=CC=C3)=CC2)N(C[C@@H]2CCO2)C2=CC(C(O)=O)=CC=C2N=1
Hazard InformationBack Directory
[Uses]

GLP-1R agonist 3 is a potent agonist of GLP-1R. GLP-1R agonist 3 is a thickened imidazole derivative compound. Glucagon-like peptide-1 (GLP-1) is an intestinal hypoglycemic hormone secreted by L-cells in the lower gastrointestinal tract. GLP-1R agonist 3 has the potential for the research of diabetes (extracted from patent WO2021197464A1, compound 1)[1].
[References]

[1] Fanglong Yang, et al. Thickened imidazole derivatives, methods of their preparation and their application in medicine. Patent WO2021197464A1.
Spectrum DetailBack Directory
[Spectrum Detail]

1H-Benzimidazole-6-carboxylic acid, 2-[[6-[(4-cyano-2-fluorophenyl)methoxy]-3',6'-dihydro[2,4'-bipyridin]-1'(2'H)-yl]methyl]-1-[(2S)-2-oxetanylmethyl]-(2428640-18-8)1HNMR
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