| Identification | Back Directory | [Name]
Methanesulfonamide, N-[4-[5-(1H-indol-4-yl)-3-pyridinyl]phenyl]- | [CAS]
2428737-31-7 | [Synonyms]
Methanesulfonamide, N-[4-[5-(1H-indol-4-yl)-3-pyridinyl]phenyl]- | [Molecular Formula]
C20H17N3O2S | [MOL File]
2428737-31-7.mol | [Molecular Weight]
363.43 |
| Chemical Properties | Back Directory | [Boiling point ]
620.6±65.0 °C(Predicted) | [density ]
1.365±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
7.76±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
PI5P4Kα-IN-1 (Compound 13) is a PI5P4Kinhibitor (IC50: 2 and 9.4 μM for PI5P4Kα and PI5P4Kβ). PI5P4Kα-IN-1 can be used for research of cancer, metabolic and immunological disorders[1]. | [References]
[1] Manz TD, et al. Discovery and Structure-Activity Relationship Study of (Z)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. J Med Chem. 2020 May 14;63(9):4880-4895. DOI:10.1021/acs.jmedchem.0c00227 |
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