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2446154-74-9

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2446154-74-9 Structure

2446154-74-9 Structure
IdentificationBack Directory
[Name]

1H-Pyrazole-4-carboxamide, 1-(4-chlorophenyl)-5-methyl-N-[(1S)-1-[2-[(methylamino)sulfonyl]-4-pyridinyl]butyl]-
[CAS]

2446154-74-9
[Synonyms]

1H-Pyrazole-4-carboxamide, 1-(4-chlorophenyl)-5-methyl-N-[(1S)-1-[2-[(methylamino)sulfonyl]-4-pyridinyl]butyl]-
[Molecular Formula]

C21H24ClN5O3S
[MDL Number]

MFCD34469290
[MOL File]

2446154-74-9.mol
[Molecular Weight]

461.96
Chemical PropertiesBack Directory
[density ]

1.36±0.1 g/cm3(Predicted)
[pka]

9.47±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

CCR1 antagonist 7 (compound 16r) is a chemokine receptor 1 (CCR1) antagonist, with an IC50 of 4 nM[1].
[References]

[1] Harcken C, et al. Discovery and optimization of pyrazole amides as antagonists of CCR1. Bioorg Med Chem Lett. 2019 Feb 1;29(3):435-440. DOI:10.1016/j.bmcl.2018.11.015
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