| Identification | Back Directory | [Name]
1H-Pyrazole-4-carboxamide, 1-(4-chlorophenyl)-5-methyl-N-[(1S)-1-[2-[(methylamino)sulfonyl]-4-pyridinyl]butyl]- | [CAS]
2446154-74-9 | [Synonyms]
1H-Pyrazole-4-carboxamide, 1-(4-chlorophenyl)-5-methyl-N-[(1S)-1-[2-[(methylamino)sulfonyl]-4-pyridinyl]butyl]- | [Molecular Formula]
C21H24ClN5O3S | [MDL Number]
MFCD34469290 | [MOL File]
2446154-74-9.mol | [Molecular Weight]
461.96 |
| Hazard Information | Back Directory | [Uses]
CCR1 antagonist 7 (compound 16r) is a chemokine receptor 1 (CCR1) antagonist, with an IC50 of 4 nM[1]. | [References]
[1] Harcken C, et al. Discovery and optimization of pyrazole amides as antagonists of CCR1. Bioorg Med Chem Lett. 2019 Feb 1;29(3):435-440. DOI:10.1016/j.bmcl.2018.11.015 |
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