| Chemical Properties | Back Directory | [density ]
1.291±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [solubility ]
DMF: 20 mg/ml
DMSO: 20 mg/ml
Ethanol: 30 mg/ml | [pka]
8.221±0.10(predicted) |
| Hazard Information | Back Directory | [Uses]
S-72 inhibits tubulin polymerization and further triggers mitosis-phase cell cycle arrest and cell apoptosis, in addition to suppressing STAT3 signaling[1]. | [References]
[1] Zhenyan Hou, et al. S-72, a Novel Orally Available Tubulin Inhibitor, Overcomes Paclitaxel Resistance via Inactivation of the STING Pathway in Breast Cancer. Pharmaceuticals (Basel). 2023 May 15;16(5):749. DOI:10.3390/ph16050749 |
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