| Identification | Back Directory | [Name]
2452396-89-1 | [CAS]
2452396-89-1 | [Synonyms]
Glucocorticoid receptor modulator-1
Glucocorticoid receptor modulator 2
N-((2R,3S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yl)-4,4-dimethyl-5-oxo-2- phenylpyrrolidin-3-yl)cyclopropanecarboxamide
Cyclopropanecarboxamide, N-[(2R,3S)-1-[1-(4-fluorophenyl)-1H-indazol-5-yl]-4,4-dimethyl-5-oxo-2-phenyl-3-pyrrolidinyl]- | [Molecular Formula]
C29H27FN4O2 | [MOL File]
2452396-89-1.mol | [Molecular Weight]
482.55 |
| Chemical Properties | Back Directory | [Boiling point ]
702.6±60.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
14.60±0.60(Predicted) | [color ]
Light brown to brown |
| Hazard Information | Back Directory | [Uses]
Glucocorticoid receptor modulator 2 (Example 1) is a glucocorticoid receptor modulator, with an IC50 value less than 100 nM. Glucocorticoid receptor modulator 2 can be used for research of inflammatory and immune diseases[1]. | [References]
[1] Florian JAKOB, et al. Substituted pyrrolidine amides iii. Patent. WO2020144375. |
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