| Identification | Back Directory | [Name]
H-GLY-TYR-PRO-GLY-LYS-PHE-NH2 | [CAS]
245443-52-1 | [Synonyms]
GYPGKF-NH2
GYPGKFAMIDE
H2N-GYPGKF-AMIDE
PAR-4 AGONIST AMIDE
PAR-4 (1-6) AMIDE (MOUSE)
H-GLY-TYR-PRO-GLY-LYS-PHE-NH2
PROTEASE-ACTIVATED RECEPTOR-4 AGONIST AMIDE
THROMBIN RECEPTOR-LIKE 3 (1-6) AMIDE (MOUSE)
PROTEINASE ACTIVATED RECEPTOR 4 (1-6) AMIDE (MOUSE)
COAGULATION FACTOR II RECEPTOR-LIKE 3 (1-6) AMIDE (MOUSE)
Glycyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide
L-Phenylalaninamide,glycyl-L-tyrosyl-L-prolylglycyl-L-lysyl-
PROTEASE ACTIVATED RECEPTOR 4 (PAR 4) (60-65) AMIDE [MUS MUSCULUS]
PAR-4 (1-6) amide (mouse) trifluoroacetate salt H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 trifluoroacetate salt
Coagulation Factor II Receptor-Like 3 (1-6) aMide (Mouse), GYPGKFaMide, Proteinase Activated Receptor 4 (1-6) aMide (Mouse), ThroMbin Receptor-Like 3 (1-6) aMide (Mouse) | [Molecular Formula]
C33H46N8O7 | [MDL Number]
MFCD08274136 | [MOL File]
245443-52-1.mol | [Molecular Weight]
666.77 |
| Chemical Properties | Back Directory | [Boiling point ]
1150.7±65.0 °C(Predicted) | [density ]
1.300±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
9.84±0.15(Predicted) | [color ]
White to off-white | [Water Solubility ]
Water : 50 mg/mL (74.99 mM) |
| Hazard Information | Back Directory | [Uses]
Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4). | [IC 50]
PAR4 | [References]
[1] Moschonas IC, et al. Molecular requirements involving the human platelet protease-activated receptor-4 mechanism of activation by peptide analogues of its tethered-ligand. Platelets. 2017 Mar 7:1-10. doi: 10.1080/09537104.2017.1282607. [Epub ahead of print] DOI:10.1080/09537104.2017.1282607
[2] Huang SC, et al. Proteinase-activated receptor-1 (PAR1) and PAR2 mediate relaxation of guinea pig internal anal sphincter. Regul Pept. 2014 Feb 10;189:46-50. DOI:10.1016/j.regpep.2014.03.001 |
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