| Identification | Back Directory | [Name]
COAGULATION FACTOR II RECEPTOR-LIKE 2 (1-6) AMIDE (MOUSE) | [CAS]
261521-21-5 | [Synonyms]
SFNGGPAMIDE
PAR-3 (1-6) AMIDE (MOUSE)
SER-PHE-ASN-GLY-GLY-PRO-NH2
H-SER-PHE-ASN-GLY-GLY-PRO-NH2
THROMBIN RECEPTOR-LIKE 2 (1-6) AMIDE (MOUSE)
PROTEINASE ACTIVATED RECEPTOR 3 (1-6) AMIDE (MOUSE)
COAGULATION FACTOR II RECEPTOR-LIKE 2 (1-6) AMIDE (MOUSE)
L-Seryl-L-phenylalanyl-L-asparaginylglycylglycyl-L-prolinamide
L-Prolinamide,L-seryl-L-phenylalanyl-L-asparaginylglycylglycyl-
SFNGGP-NH2 PAR3 Tethered Ligand (Murine) / Activates PAR1 and PAR2
L-Prolinamide, L-seryl-L-phenylalanyl-L-asparaginylglycylglycyl- (9CI)
Proteinase Activated Receptor 3 (1-6) aMide (Mouse), SFNGGPaMide, ThroMbin Receptor-Like 2 (1-6) aMide (Mouse), Coagulation Factor II Receptor-Like 2 (1-6) aMide (Mouse) | [Molecular Formula]
C25H36N8O8 | [MDL Number]
MFCD08702740 | [MOL File]
261521-21-5.mol | [Molecular Weight]
576.6 |
| Hazard Information | Back Directory | [Uses]
SFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the cutaneous mast cells of humans. Protease-Activated Receptors (PARs) have been studied for their roles in itch and their itch-associated response through histamine-dependent/independent pathways have been reported. PAR-3 has been shown not to induce itching alone but possibly in conjunction with PAR-4. Co-expression of PAR-3 and PAR-4 enhances thrombin action suggesting that PAR-3 alone does not mediate transmembrane signaling but instead functions as a cofactor to activate PAR-4.) |
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