| Identification | Back Directory | [Name]
5-Methyl-2-thioxylouridine | [CAS]
246857-26-1 | [Synonyms]
5-Methyl-2-thioxylouridine
5-Methyl-2-thio-arabinouridine
1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one | [Molecular Formula]
C10H14N2O5S | [MOL File]
246857-26-1.mol | [Molecular Weight]
274.29 |
| Hazard Information | Back Directory | [Uses]
5-Methyl-2-thio-xylo-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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