| Identification | Back Directory | [Name]
1-(4'-thio-beta-ribofuranosyl)thymine | [CAS]
6741-71-5 | [Synonyms]
5-Methyl-4'-thiouridine
Uridine, 5-methyl-4'-thio-
1-(4'-thio-beta-ribofuranosyl)thymine
Uridine,5-methyl-4'-thio- (7CI,8CI,9CI)
1-(4-thio-beta-D-ribofuranosyl)-5-Methyluracil
5-Methyl-4’-thiouridine, 1-(4-thio-beta-D-ribofuranosyl)-5-methyluracil
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-methylpyrimidine-2,4-dione
1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione | [Molecular Formula]
C10H14N2O5S | [MDL Number]
MFCD27921041 | [MOL File]
6741-71-5.mol | [Molecular Weight]
274.29 |
| Hazard Information | Back Directory | [Uses]
N6-Methyl-2-methyl thioadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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