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2474076-02-1

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2474076-02-1 Structure

2474076-02-1 Structure
IdentificationBack Directory
[Name]

RapaBlock
[CAS]

2474076-02-1
[Synonyms]

RapaBlock
[Molecular Formula]

C49H74N2O13
[MOL File]

2474076-02-1.mol
[Molecular Weight]

899.12
Chemical PropertiesBack Directory
[Boiling point ]

987.640±75.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.272±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

9.966±0.70(predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

RapaBlock is a potent, non-immunosuppressive and brain-impermeable FKBP12 ligand[1].
[References]

[1] Ziyang Zhang, et al. Brain-restricted mTOR inhibition with binary pharmacology. Nature. 2022 Sep;609(7928):822-828. DOI:10.1038/s41586-022-05213-y
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