| Identification | Back Directory | [Name]
1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)- | [CAS]
2477650-96-5 | [Synonyms]
USP8-IN-1
1-Piperazinecarbothioamide, 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)- | [Molecular Formula]
C18H21N5O3S | [MOL File]
2477650-96-5.mol | [Molecular Weight]
387.46 |
| Chemical Properties | Back Directory | [Boiling point ]
603.0±65.0 °C(Predicted) | [density ]
1.397±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 125 mg/mL (322.61 mM; Need ultrasonic) | [form ]
Solid | [pka]
12.72±0.20(Predicted) | [color ]
Light yellow to green yellow |
| Hazard Information | Back Directory | [Biological Activity]
USP8-IN-1 is a USP8 inhibitor with an IC50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI50 of 82.04 μM (CN111138358A; U10)[1]. | [References]
[1]. Zhiyu Li, et al. USP8 inhibitor and preparation method and application thereof. CN111138358A. |
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