| Identification | Back Directory | [Name]
[(2R)-2,3-di(octadecanoyloxy)propyl] 2-(2-methoxyethoxycarbonylamino)ethyl phosphate | [CAS]
247925-28-6 | [Synonyms]
MPEG2000-DSPE Sodium Salt
[(2R)-2,3-di(octadecanoyloxy)propyl] 2-(2-methoxyethoxycarbonylamino)ethyl phosphate
1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol) sodium salt | [Molecular Formula]
C45H88NO11P | [MOL File]
247925-28-6.mol | [Molecular Weight]
850.154 |
| Chemical Properties | Back Directory | [solubility ]
Chloroform: 10 mg/ml
DMF: 2.5 mg/ml
DMF: PBS (pH 7.2) (1:1): 0.5 mg/ml | [solubility ]
DMF: Slightly soluble
Water: Slightly soluble | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
18:0 mPEG2000 PE sodium (DSPE-mPEG2000 (sodium)) is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery[1][2]. | [References]
[1] Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013;10(6):781-811. DOI:10.1586/17434440.2013.855471
[2] Zhang L, et al. DSPE-mPEG2000-Modified Podophyllotoxin Long-Circulating Liposomes for Targeted Delivery: Their Preparation, Characterization, and Evaluation. Curr Drug Deliv. 2025 Jan 2. DOI:10.2174/0115672018356666241224052638 |
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