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247925-28-6

247925-28-6 Structure

247925-28-6 Structure
IdentificationBack Directory
[Name]

[(2R)-2,3-di(octadecanoyloxy)propyl] 2-(2-methoxyethoxycarbonylamino)ethyl phosphate
[CAS]

247925-28-6
[Synonyms]

MPEG2000-DSPE Sodium Salt
[(2R)-2,3-di(octadecanoyloxy)propyl] 2-(2-methoxyethoxycarbonylamino)ethyl phosphate
1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol) sodium salt
[Molecular Formula]

C45H88NO11P
[MOL File]

247925-28-6.mol
[Molecular Weight]

850.154
Chemical PropertiesBack Directory
[solubility ]

Chloroform: 10 mg/ml
DMF: 2.5 mg/ml
DMF: PBS (pH 7.2) (1:1): 0.5 mg/ml
[solubility ]

DMF: Slightly soluble
Water: Slightly soluble
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

18:0 mPEG2000 PE sodium (DSPE-mPEG2000 (sodium)) is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery[1][2].
[References]

[1] Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013;10(6):781-811. DOI:10.1586/17434440.2013.855471
[2] Zhang L, et al. DSPE-mPEG2000-Modified Podophyllotoxin Long-Circulating Liposomes for Targeted Delivery: Their Preparation, Characterization, and Evaluation. Curr Drug Deliv. 2025 Jan 2. DOI:10.2174/0115672018356666241224052638
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