2479276-17-8

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2479276-17-8 Structure

Identification	Back Directory
[Name] 1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine Trihydrochloride
[CAS] 2479276-17-8
[Synonyms] 1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine Trihydrochloride
[Molecular Formula] C18H26ClN5
[MOL File] 2479276-17-8.mol
[Molecular Weight] 347.89

Chemical Properties	Back Directory
[storage temp. ] 4°C, away from moisture
[solubility ] DMSO : 125 mg/mL (297.05 mM; Need ultrasonic)
[form ] Solid
[color ] White to yellow

Hazard Information	Back Directory
[Biological Activity] AXC-715 (T785) trihydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1[1]. AXC-715 trihydrochloride, compound D from WO2020190734A1, can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants[2].
[References] [1]. Sung-Ju Moon, et al. Compositions containing, methods and uses of antibody-tlr agonist conjugates. Patent WO2020168017A1.[2]. Shelley Erin ACKERMAN, et al. Immunoconjugates targeting pd-l1. Patent WO2020190734A1.

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