| Identification | Back Directory | [Name]
Pyridine, 3-[2-[(4-chloro-1-naphthalenyl)oxy]ethyl]-, 1-oxide | [CAS]
2487253-25-6 | [Synonyms]
Pyridine, 3-[2-[(4-chloro-1-naphthalenyl)oxy]ethyl]-, 1-oxide | [Molecular Formula]
C17H14ClNO2 | [MOL File]
2487253-25-6.mol | [Molecular Weight]
299.75 |
| Chemical Properties | Back Directory | [Melting point ]
93-94 °C | [Boiling point ]
556.9±35.0 °C(Predicted) | [density ]
1.22±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
0.79±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
DL-175 (compound 13) is a selective GPR84 agonist with biased agonistic activity. DL-175 can selectively activate functional responses in immune cells and induce enhanced chemotaxis and phagocytosis of human bone marrow cells. DL-175 is a potential chemical probe[1]. | [References]
[1] Lucy D, et al. A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages. ACS Chem Biol. 2019 Sep 20;14(9):2055-2064. DOI:10.1021/acschembio.9b00533 |
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