| Identification | Back Directory | [Name]
Benzoic acid, 3-[[2-chloro-4-(trifluoromethyl)phenoxy]methyl]-2-fluoro- | [CAS]
2492595-24-9 | [Synonyms]
MRGPRX4 modulator-2
3-[[2-chloro-4-(trifluoromethyl)phenoxy]methyl]-2-fluoro-benzoic acid
Benzoic acid, 3-[[2-chloro-4-(trifluoromethyl)phenoxy]methyl]-2-fluoro- | [Molecular Formula]
C15H9ClF4O3 | [MOL File]
2492595-24-9.mol | [Molecular Weight]
348.68 |
| Chemical Properties | Back Directory | [Boiling point ]
425.5±45.0 °C(Predicted) | [density ]
1.475±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.19±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s Syndrome, and other chronic itch conditions[1]. | [References]
[1] Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537A1 (compound 1-55) |
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