| Identification | Back Directory | [Name]
Urea, N'-[4-(3,5-difluorophenoxy)-2-pyridinyl]-N-ethyl-N-[(2R)-3,3,3-trifluoro-2-hydroxypropyl]- | [CAS]
2642346-30-1 | [Synonyms]
MrgprX2 antagonist-2
Urea, N'-[4-(3,5-difluorophenoxy)-2-pyridinyl]-N-ethyl-N-[(2R)-3,3,3-trifluoro-2-hydroxypropyl]- | [Molecular Formula]
C17H16F5N3O3 | [MOL File]
2642346-30-1.mol | [Molecular Weight]
405.32 |
| Chemical Properties | Back Directory | [Boiling point ]
533.2±50.0 °C(Predicted) | [density ]
1.435±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
11.67±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
MrgprX2 antagonist-2 is an MrgprX2 antagonist extracted from patent WO2021092262A1, example E163. MrgprX2 antagonist-2 can be used for the research of inflammatory disorders of the skin[1]. | [References]
[1] CEVIKBAS F, et, al. Mrgprx2 antagonists and uses thereof. WO2021092262A1.
[2] Porebski G, et, al. Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions. Front Immunol. 2018 Dec 20;9:3027. DOI:10.3389/fimmu.2018.03027 |
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