| Identification | More | [Name]
5-Chloro-2-mercaptobenzimidazole | [CAS]
25369-78-2 | [Synonyms]
5-CHLORO-2-BENZIMIDAZOLETHIOL
5-CHLORO-2-MERCAPTOBENZIMIDAZOLE
5-CHLOROBENZIMIDAZOLE-2-THIOL
6-CHLORO-1H-BENZIMIDAZOLE-2-THIOL
6-CHLORO-1H-BENZO[D]IMIDAZOLE-2-THIOL
AKOS BBS-00000469
ASISCHEM D51128
TIMTEC-BB SBB003718
5-chloro-2(3)-benzimidazolethione
5-chloro-2-benzimidazolinethion
5-chloro-1,3-dihydro-2H-benzimidazole-2-thione
5-Chloro-2-Mercato Benzimidazole
5-Chlorobenzimidazole-2-thiol,98%
2H-Benzimidazole-2-thione,5-chloro-1,3-dihydro-(9CI)
5-Choro-2-Mercaptobenzimidazole
5-CHLORO-2-MERCAPTOBENZIMIDAZOLE 98%
2-Mercapto-5-chloro-1H-benzimidazole
5-Chloro-1H-benzimidazole-2-thiol
6-Chloro-2-mercapto-1H-benzimidazole | [EINECS(EC#)]
246-903-5 | [Molecular Formula]
C7H5ClN2S | [MDL Number]
MFCD01044385 | [Molecular Weight]
184.65 | [MOL File]
25369-78-2.mol |
| Chemical Properties | Back Directory | [Appearance]
white to yellowish crystalline powder | [Melting point ]
290-292 °C | [Boiling point ]
300.7±44.0 °C(Predicted) | [density ]
1.4750 (rough estimate) | [refractive index ]
1.6100 (estimate) | [storage temp. ]
Storage temp. 2-8°C | [form ]
powder to crystal | [pka]
9.71±0.30(Predicted) | [color ]
White to Light yellow to Light orange | [Sensitive ]
Air Sensitive | [InChI]
1S/C7H5ClN2S/c8-4-1-2-5-6(3-4)10-7(11)9-5/h1-3H,(H2,9,10,11) | [InChIKey]
ZZIHEYOZBRPWMB-UHFFFAOYSA-N | [SMILES]
ClC1=CC=C2N([H])C(S[H])=NC2=C1 | [CAS DataBase Reference]
25369-78-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
T,Xi | [Risk Statements ]
R25:Toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN2811 | [WGK Germany ]
WGK 3 | [RTECS ]
DE1605000 | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29339980 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2 | [Toxicity]
mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04403, |
| Hazard Information | Back Directory | [Chemical Properties]
white to yellowish crystalline powder | [Uses]
Tyrosinase-IN-22 (compound 4) is an inhibitor of tyrosinase substrates (L-tyrosine and L-dopa) with IC50s of 60 nM and 30 nM, respectively. Tyrosinase-IN-22 also shows potent antioxidant and anti-melanogenic properties, thus can be used for relevant researches[1]. | [References]
[1] Yoon D, et al. In vitro and in vivo anti-pigmentation effects of 2-mercaptobenzimidazoles as nanomolar tyrosinase inhibitors on mammalian cells and zebrafish embryos: Preparation of pigment-free zebrafish embryos. Eur J Med Chem. 2024 Feb 15;266:116136. DOI:10.1016/j.ejmech.2024.116136 |
|
| Company Name: |
Alfa Aesar
|
| Tel: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|