| Identification | Back Directory | [Name]
C12 NBD-SPHINGOMYELIN | [CAS]
254117-01-6 | [Synonyms]
C12 NBD-SPHINGOMYELIN
FLUORESCENT SPHINGOMYELIN
N-(NBD-AMINOLAUROYL)SPHINGOMYELIN
C12-NBD-SPHINGOMYELIN, FLUORESCENT
N-C12-NBD-SPHINGOSYLPHOSPHORYLCHOLINE
N-DODECANOYL-NBD-SPHINGOSYLPHOSPHORYLCHOLINE
N-(12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL)-SPHINGOSINE-1-PHOSPHOCHOLINE
N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGOSINE-1-PHOSPHOCHOLINE;C12-NBD SPHINGOMYELIN | [Molecular Formula]
C41H73N6O9P | [MDL Number]
MFCD02259246 | [MOL File]
254117-01-6.mol | [Molecular Weight]
825.03 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [form ]
Solid | [pka]
1.203±0.50(predicted) | [color ]
Yellow to orange | [InChIKey]
FCQMKLRMKNYONQ-YPGNEAGUSA-N | [SMILES]
[P](=O)([O-])(OC[C@H](NC(=O)CCCCCCCCCCCNc1c2n[o]nc2c(cc1)[N+](=O)[O-])[C@H](O)\C=C\CCCCCCCCCCCCC)OCC[N+](C)(C)C |
| Hazard Information | Back Directory | [Uses]
C12-NBD-sphingomyelin has been used as a substrate to test substrate specificity of neutral ceramidase orthologue encoded by AsahA gene. | [Biological Activity]
Sphingomyelin (SM) is produced from phosphatidylcholine and ceramide on the cell surface and in lumen of the Golgi. SMμs high packing density and affinity to sterols form a rigid barrier to the extracellular environment. SM is also involved in the formation of lipid rafts in cell membraneswhich perform important functions in signal transduction and membrane trafficking. |
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