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2561476-24-0

2561476-24-0 Structure

2561476-24-0 Structure
IdentificationBack Directory
[Name]

EMAC10101d
[CAS]

2561476-24-0
[Synonyms]

EMAC10101d
[Molecular Formula]

C17H15Cl2N3O2S2
[MDL Number]

MFCD34165711
[MOL File]

2561476-24-0.mol
[Molecular Weight]

428.36
Chemical PropertiesBack Directory
[Boiling point ]

614.5±65.0 °C(Predicted)
[density ]

1.50±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

10.24±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

EMAC10101d is a potent and selective inhibitor of Carbonic Anhydrase Isoform toward hCA II with an inhibitory activity in the low nanomolar range.
[Uses]

EMAC10101d is a potent and selective toward hCA II inhibitor, with a Ki of 8.1 nM[1].
[IC 50]

CA Ⅱ
[References]

[1] Rita Meleddu, et al. New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII. ACS Med Chem Lett. 2020 Feb 13;11(5):852-856. DOI:10.1021/acsmedchemlett.9b00644
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