| Chemical Properties | Back Directory | [Boiling point ]
623.189±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.571±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
13.235±0.10(predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
AEP-IN-2 is an asparagine endopeptidase (AEP) inhibitor via block AEP cleavage of APP and Tau. AEP-IN-2 has oral activity and decreases Aβ40 and Aβ42 and p-Tau levels [1]. | [References]
[1] Zhengjiang Qian, et al. Inhibition of asparagine endopeptidase (AEP) effectively treats sporadic Alzheimer's disease in mice. Neuropsychopharmacology. 2023. DOI:10.1038/s41386-023-01774-2 |
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