| Identification | Back Directory | [Name]
2-Propylthiazolo[4,5-c]quinolin-4-aMine | [CAS]
256922-53-9 | [Synonyms]
CL075
CL075 >=98% (HPLC)
2-Propylthiazolo[4,5-c]quinolin-4-aMine
Thiazolo[4,5-c]quinolin-4-amine, 2-propyl- | [Molecular Formula]
C13H13N3S | [MDL Number]
MFCD09998898 | [MOL File]
256922-53-9.mol | [Molecular Weight]
243.33 |
| Chemical Properties | Back Directory | [Boiling point ]
440.1±25.0 °C(Predicted) | [density ]
1.313±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Soluble in DMSO | [form ]
powder | [pka]
4.23±0.50(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
CL075 has been used to activate the monocyte-derived dendritic cells (DCs) to demonstrate the ability of DCs to induce cell death. | [Biological Activity]
CL075 is a selective agonist of Toll-like receptor-8 (TLR-8) with immunostimulant activity. It showed an EC50 value of 400nM for IRF-NFΚB stimulation in TLR8 compared to 4 μM for TLR7.''CL075 is a thiazoloquinolone derivative. It might influence tumor development. | [in vivo]
CL075 (5 μM (0.5 mL); s.c.) activates a mild antigen-specific antibody response in rabbits[1]. | [IC 50]
TLR8 | [storage]
Store at +4°C |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|