| Identification | Back Directory | [Name]
Acetamide, N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[[4-(3-methylphenyl)-5-(4-methylphenyl)-4H-1,2,4-triazol-3-yl]thio]- | [CAS]
2569598-01-0 | [Synonyms]
NRP1 antagonist 1
Acetamide, N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[[4-(3-methylphenyl)-5-(4-methylphenyl)-4H-1,2,4-triazol-3-yl]thio]- | [Molecular Formula]
C22H22N6OS2 | [MOL File]
2569598-01-0.mol | [Molecular Weight]
450.58 |
| Hazard Information | Back Directory | [Uses]
NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research[1]. | [References]
[1] Kewen Peng, et al. Discovery of novel nonpeptide small-molecule NRP1 antagonists: Virtual screening, molecular simulation and structural modification. Bioorg Med Chem. 2020 Jan 1;28(1):115183. DOI:10.1016/j.bmc.2019.115183 |
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