| Identification | More | [Name]
3-AMINOBENZOYLMETHYLAMIDE | [CAS]
25900-61-2 | [Synonyms]
3-AMINOBENZOYLMETHYLAMIDE
3-AMINO-N-METHYLBENZAMIDE
BUTTPARK 25\02-27
Benzamide, 3-amino-N-methyl-(9CI)
3-AMINOBENZOYLMETHYLAMIDE 98+%
N-Methyl-3-aminobenzamide | [EINECS(EC#)]
233-675-7 | [Molecular Formula]
C8H10N2O | [MDL Number]
MFCD00070630 | [Molecular Weight]
150.18 | [MOL File]
25900-61-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
119°C | [Boiling point ]
346.7±25.0 °C(Predicted) | [density ]
1.137±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
powder to crystaline | [pka]
15.19±0.46(Predicted) | [color ]
White to Light yellow to Light red | [CAS DataBase Reference]
25900-61-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3 | [HS Code ]
2924.29.7790 | [HazardClass ]
IRRITANT |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 3-amino-N-methylbenzamide from N-methyl-3-nitrobenzamide: A mixture of N-methyl-3-nitrobenzamide (2.47 g, 13.71 mmol) with 10% Pd/C catalyst (0.5 g) in methanol (50 mL) was subjected to hydrogenation at room temperature and atmospheric pressure overnight. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filtrate was subsequently concentrated. The resulting crude product was used directly in the subsequent reaction steps without further purification. (Yield: 2.06 g, 100%) | [References]
[1] Patent: US2004/97493, 2004, A1. Location in patent: Page/Page column 24
[2] Patent: US2010/160323, 2010, A1. Location in patent: Page/Page column 54
[3] Journal of Chemical Research, 2006, # 4, p. 223 - 224
[4] Patent: US5589489, 1996, A
[5] Patent: EP2774918, 2014, A1. Location in patent: Paragraph 0126; 0133 |
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