| Identification | Back Directory | [Name]
2-(4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)acetic acid | [CAS]
2591180-39-9 | [Synonyms]
2-(4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)acetic acid | [Molecular Formula]
C19H20N4O6 | [MOL File]
2591180-39-9.mol | [Molecular Weight]
400.39 |
| Chemical Properties | Back Directory | [Boiling point ]
723.1±60.0 °C(Predicted) | [density ]
1.498±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
powder | [pka]
10.83±0.40(Predicted) |
| Hazard Information | Back Directory | [Description]
Pomalidomide-piperazine-acetic acid is a functionalized cereblon ligand for development of pomalidomide-based ProTACs. Pomalidomide-piperazine-acetic acid allows rapid conjugation with amine linkers due to the presence of a carboxyl group via peptide coupling reactions. |
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