| Identification | Back Directory | [Name]
5'-IODO-5'-DEOXYTHYMIDINE | [CAS]
25953-14-4 | [Synonyms]
5'-IODO-5'-DEOXYTHYMIDINE
5'-Deoxy-5'-iodothymidine
5'-Deoxy-5'-iodo-D-thymidine
Thymidine, 5'-deoxy-5'-iodo-
1-[4-HYDROXY-5-(IODOMETHYL)OXOLAN-2-YL]-5-METHYL-3H-PYRIMIDINE-2,4-DIONE
1-((2R,4S,5S)-4-hydroxy-5-(iodomethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione | [Molecular Formula]
C10H13IN2O4 | [MDL Number]
MFCD04973690 | [MOL File]
25953-14-4.mol | [Molecular Weight]
352.13 |
| Hazard Information | Back Directory | [Uses]
5′-Deoxy-5′-iodothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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