| Identification | Back Directory | [Name]
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethyl]amino]- | [CAS]
2599846-07-6 | [Synonyms]
Pomalidomide-NH-PEG2-Tos
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethyl]amino]-
2-(2-[(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)amino]ethoxy)ethyl 4-methylbenzene-1-sulfonate | [Molecular Formula]
C24H25N3O8S | [MOL File]
2599846-07-6.mol | [Molecular Weight]
515.54 |
| Hazard Information | Back Directory | [Uses]
Pomalidomide-PEG2-Tos is an E3 ligase ligand-linker conjugates, composed of a cereblon ligand and two-unit PEG linker[1]. | [IC 50]
Cereblon | [References]
[1] Su S, et al. Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders. J Med Chem. 2019 Aug 22;62(16):7575-7582. DOI:10.1021/acs.jmedchem.9b00871 |
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| Company Name: |
Pharmalego
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| Tel: |
18321033991 |
| Website: |
https://cn.pharmalego.com/ |
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