| Identification | Back Directory | [Name]
1H-Benzimidazol-2-amine, N-methyl-1-[4-[(3R)-3-methyl-4-morpholinyl]-6-[3-methyl-1-(4-piperidinyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]- | [CAS]
2601571-19-9 | [Synonyms]
ATR-IN-5
1H-Benzimidazol-2-amine, N-methyl-1-[4-[(3R)-3-methyl-4-morpholinyl]-6-[3-methyl-1-(4-piperidinyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]- | [Molecular Formula]
C27H32F3N9O | [MOL File]
2601571-19-9.mol | [Molecular Weight]
555.6 |
| Hazard Information | Back Directory | [Uses]
ATR-IN-5 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-5 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent CN112047938A, compound D24)[1]. | [References]
[1] Zhao, Yanping, et al. 2,4,6-Trisubstituted pyrimidine compounds as atr kinase inhibitors. Patent CN112047938A. |
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