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Zavolosotine (Compound 1) is an orally active agonist for somatostatin receptor type 5 (SST5) with EC50 <1 nM. Zavolosotine inhibits insulin and glucagon secretion, increases levels of glucagon in blood in rat model[1]. | [References]
[1] FERRARA-COOK C, et al., Somatostatin receptor type 5 agonist for the treatment of hyperinsulinism. WO2022177988 . |
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ChemOrigin Pharm
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