| Identification | Back Directory | [Name]
Pyrido[3,2-d]pyrimidine-7-carboxamide, 4-[[(1R)-1-[(acetylamino)methyl]-1-methylpentyl]amino]-2-amino-N,N-dimethyl- | [CAS]
2616605-55-9 | [Synonyms]
TLR8 agonist 6
Pyrido[3,2-d]pyrimidine-7-carboxamide, 4-[[(1R)-1-[(acetylamino)methyl]-1-methylpentyl]amino]-2-amino-N,N-dimethyl- | [Molecular Formula]
C19H29N7O2 | [MOL File]
2616605-55-9.mol | [Molecular Weight]
387.48 |
| Hazard Information | Back Directory | [Uses]
TLR8 agonist 6 (Compound A) is a TLR8 agonist, with an EC50 of 0.052 μM. TLR8 agonist 6 induces IL-12p40 production in human PBMC (EC50: 0.031 μM). TLR8 agonist 6 can be used in the research of virus resistance, infection resistance, autoimmunity, tumor, etc[1]. | [References]
[1] Liang Bo, et al. 2-aminopyrimidine compounds and pharmaceutical composition and application thereof. Patent. CN112390795. |
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