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2623-23-6

2623-23-6 Structure

2623-23-6 Structure
IdentificationMore
[Name]

(1R)-(-)-Menthyl acetate
[CAS]

2623-23-6
[Synonyms]

(-)-(1R)-MENTHYL ACETATE
(1R)-(-)-MENTHYL ACETATE
(-)-ACETOXY-P-MENTHANE
FEMA 2668
L-MENTHYL ACETATE
(-)-MENTHYL ACETATE
MENTHYL ACETATE
MENTHYL ACETATE, L-
(R)-(-)-MENTHYL ACETATE
2-isopropyl-5-methyl-,acetate,l-cyclohexan-1-o
5-methyl-2-(1-methylethyl)-,acetate,[1R-(1.alpha.,2.beta.,5.alpha.)]-Cyclohexanol
acetate,(1r,3r,4s)-(-)-mentho
aceticacid(1R)-menthylester
cyclohexanol,5-methyl-2-(1-methylethyl)-,acetate,(1r-(1alpha,2beta,5alpha)
cyclohexanol,5-methyl-2-(1-methylethyl)-,acetate,[1theta-(1alpha,2beta,5
l-p-menth-3-ylacetate
p-menth-3-ylester,l-aceticaci
Acetoxymenthane
L-MENTHYL ACETATE 98+% NATURAL FCC
(-)-(1R)-MENTHYL ACETATE, TERPENE STANDA RD
[EINECS(EC#)]

220-076-0
[Molecular Formula]

C12H22O2
[MDL Number]

MFCD00001482
[Molecular Weight]

198.3
[MOL File]

2623-23-6.mol
Chemical PropertiesBack Directory
[Melting point ]

<25 °C
[alpha ]

-81°(20/D, c=8, C6H6)
[Boiling point ]

229-230 °C(lit.)
[density ]

0.92 g/mL at 25 °C(lit.)
[vapor pressure ]

45Pa at 20℃
[FEMA ]

2668
[refractive index ]

n20/D 1.447(lit.)
[Fp ]

171 °F
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

neat
[color ]

Colourless
[Specific Gravity]

0.922
[Odor]

at 100.00 %. mentholic minty herbal tea fruity woody floral earthy
[Odor Type]

mentholic
[Optical Rotation]

[α]20/D 81°, c = 8 in benzene
[Water Solubility ]

23.2mg/L at 20℃
[JECFA Number]

431
[Merck ]

14,5839
[BRN ]

2208505
[Major Application]

flavors and fragrances
[InChI]

1S/C12H22O2/c1-8(2)11-6-5-9(3)7-12(11)14-10(4)13/h8-9,11-12H,5-7H2,1-4H3/t9-,11+,12-/m1/s1
[InChIKey]

XHXUANMFYXWVNG-ADEWGFFLSA-N
[SMILES]

CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(C)=O
[LogP]

4.39 at 25℃
[CAS DataBase Reference]

2623-23-6(CAS DataBase Reference)
[EPA Substance Registry System]

2623-23-6(EPA Substance)
Safety DataBack Directory
[Safety Statements ]

S24/25:Avoid contact with skin and eyes .
[RIDADR ]

NA 1993 / PGIII
[WGK Germany ]

3
[RTECS ]

AI5900000
[TSCA ]

Yes
[HS Code ]

2915 39 00
[REACH Registrations]

Active
[Storage Class]

10 - Combustible liquids
[Hazard Classifications]

Aquatic Chronic 2
[Safety Profile]

Low toxicity by ingestion and skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
[Toxicity]

LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 5000 mg/kg
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium acetate-->Peppermint oil
Hazard InformationBack Directory
[Chemical Properties]

(1R)-(-)-Menthyl acetate occurs in peppermint oils. It is a colorless liquid with a fresh, fruity, peppermint odor.
(?)-Menthyl acetate is prepared by acetylation of (?)-menthol (e.g., with acetic anhydride). It is used mainly in peppermint flavors and reconstituted peppermint oils, but also to a small extent in perfumery.
[Uses]

L-Menthyl Acetate, and its derivatives, is used as a penetration enhancers, to enhance the skin permeation of various drugs with differing lipophilicities, such as 5-aminolevulinic acid (ALA), 5-fluorouracil (5-FU), isosorbide dinitrate (ISDN), lidocaine (LD), etc.
[Definition]

ChEBI: (-)-Menthyl acetate is a p-menthane monoterpenoid.
[Flammability and Explosibility]

Notclassified
[Biochem/physiol Actions]

Taste at 25 ppm
[Synthesis]

L-Menthyl acetate is produced by direct esterification of racemicMenthol with Acetic acid under azeotropic conditions.
Spectrum DetailBack Directory
[Spectrum Detail]

L-Menthyl acetate(2623-23-6)MS
L-Menthyl acetate(2623-23-6)1HNMR
L-Menthyl acetate(2623-23-6)IR1
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

(1R)-(-)-Menthyl acetate, 98%(2623-23-6)
[Sigma Aldrich]

2623-23-6(sigmaaldrich)
[TCI AMERICA]

(-)-Menthyl Acetate,>98.0%(GC)(2623-23-6)
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