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2639874-49-8

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2639874-49-8 Structure

2639874-49-8 Structure
IdentificationBack Directory
[Name]

Mc-Leu-Gly-Arg
[CAS]

2639874-49-8
[Synonyms]

[Molecular Formula]

C21H34N6O6
[MOL File]

2639874-49-8.mol
[Molecular Weight]

466.53
Chemical PropertiesBack Directory
[density ]

1.36±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

3.35±0.10(predicted)
Hazard InformationBack Directory
[Uses]

Mc-Leu-Gly-Arg is a cleavable ether linker for antibody-drug conjugates (ADC) design.
[IC 50]

Cleavable Linker
[References]

[1] Zhang D, et al. Immolation of p-Aminobenzyl Ether Linker and Payload Potency and Stability Determine the Cell-Killing Activity of Antibody-Drug Conjugates with Phenol-Containing Payloads. Bioconjug Chem. 2018 Feb 21;29(2):267-274. DOI:10.1021/acs.bioconjchem.7b00576
2639874-49-8 suppliers list
Company Name: Henan Mengtai Pharmaceutical Technology Co., Ltd  
Tel: 17634413542
Website: https://www.henanmengtai.com
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