| | Identification | Back Directory |  | [Name] 
 BETA-NADPH TETRASODIUM SALT
 |  | [CAS] 
 2646-71-1
 |  | [Synonyms] 
 TPNH
 NADPH
 TPNH,NA4
 TPNH2 NA4
 NADPH NA4
 NADPH 4NA
 BETA-NADPH
 IINADP-4NA
 2′-NADPH hydrate
 NADPH TETRASODIUM
 2'-TPNH, TETRASODIUM
 NADPH Na4
 TPNH TETRASODIUM SALT
 2'-NADPH, TETRASODIUM
 NADPH TETRASODIUM SALT
 BETA-NADPH, TETRASODIUM
 2'-TPNH TETRASODIUM SALT
 2'-NADPH TETRASODIUM SALT
 BETA-NADPH TETRASODIUM SALT
 coenzyme ii tetrasodium salt
 NADPH Tetrasodium Salt Hydrate
 TPNH2 Na4
 NADP.Na4anhydrousortetrahydrate
 NADPH, REDUCED FORM, TETRASODIUM
 NADPH tetrasodium salt, pure, 95%
 NADPH TETRASODIUM SALT, 95%, PURE
 NADPH tetrasodium salt, extra pure
 beta-Triphosphopyridine nucleotide
 TPNH TETRASODIUM SALT,REDUCED FORM
 NADPH TETRASODIUM SALT TETRAHYDRATE
 COENZYME II REDUCED TETRASODIUM SALT
 COENZYME II RED FORM TETRASODIUM SALT
 Triphosphopyridine nucleotide reduced
 BETA-NADPH TETRASODIUM SALT,REDUCED FORM
 BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE P
 BETA-NAD PHOSPHATE REDUCED FORM TETRASOD
 NADPH tetrasodium salt,ca. 98%,extra pure
 COENZYME II TETRASODIUM SALT,REDUCED FORM
 nicotinamide adenine dinucleoside phosphate
 NADPH tetrasodium salt, extra pure, ca. 98%
 Coenzyme II reduced tetrasodium salt(NADPH)
 NADPH tetrasodium salt hydrate, approx. 98%
 β-Nicotinamide adenine dinucleotide 2′-phosp
 CoenzyMe II Reduced TetrasodiuM Salt Hydrate
 NADPH tetrasodiuM salt hydrate, 96%, extra pure
 CoenzyMe II reduced tetrasodiuM salt
(NADPH 4Na)
 beta-NADP, reduced form, tetrasodium salt Type I
 beta-triphosphopyridine nucleotide tetrasodium salt
 TRIPHOSPHOPYRIDINE NUCLEOTIDE (REDUCED) SODIUM SALT
 B-NICOTINAMIDE ADENINE DINUCLEOTIDE*3'-P HOSPHATE RE
 TRIPHOSPHOPYRIDINE NUCLEOTIDE REDUCED TETRASODIUM SALT
 TRIPHOSPHOPYRIDINE NUCLEOTIDE, REDUCED FORM, TETRASODIUM
 BETA-TRIPHOSPHOPYRIDINE NUCLEOTIDE, SODIUM, REDUCED FORM
 TRIPHOSPYRIDINE NUCLEOTIDE, REDUCED FORM TETRASODIUM SALT
 BETA-NICOTINAM. ADEN. DINUCL. PHOS. RED.  4SO-SALT,10 X 5 MG
 BETA-NICOTINAMIDE ADENINE DINUCLEO.PHOS- PHATE RED. NA4-SALT
 TRIPHOSPHOPYRIDINE NUCLEOTIDE, REDUCED FORM TETRASODIUM SALT
 Nicotinamide adenine dinucleotide phosphate reduced -Na4-salt
 BETA-NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE, REDUCED, 4NA
 Triphosphopyridine Nucleotide Reduced TetrasodiuM Salt Hydrate
 BETA-TRIPHOSPHOPYRIDINE NUCLEOTIDE TETRASODIUM SALT,REDUCED FORM
 BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCED NA4-SALT
 REDUCED NICOTINAMIDE ADENOSINE DINUCLEOTIDE PHOSPHATE TETRASODIUM
 NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED) SODIUM SALT
 beta-nicotinamide adenine dinucleotide phosphate tetrasodium salt
 Nicotinamide-adenine dinucleotide,reduced form (tetrasodium salt)
 DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE TETRASODIUM SALT
 BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM) 4NA
 NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE TETRASODIUM SALT, REDUCED
 BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCED TETRASODIUM SALT
 β-nicotinamide adenine dinucleotide 2'-phosphate reduced tetrasodium salt
 BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT, REDUCED FORM
 B-NICOTINAMIDE ADENINE DINUCLEOTIDE 3'-PHOSPHATE, REDUCED, TETRASODIUM SALT
 NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM) TETRASODIUM SALT
 β-Nicotinamide adenine dinucleotide phosphate tetrasodium salt,reduced form
 DihydronicotinaMide Adenine Dinucleotide Phosphate TetrasodiuM Salt Hydrate
 b-Nicotinamide adenine dinucleotide phosphate reduced form, tetrasodium salt
 NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCED (NADPH2) TETRASODIUM SALT
 NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCED TETRASODIUM SALT extrapure
 BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE, REDUCED FORM TETRASODIUM SALT
 BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE TETRASODIUM SALT (REDUCED FORM)
 Nicotinamide adenine dinucleotide phosphate >98% (reduced form) tetrasodium salt
 BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCED, TETRASODIUM SALT, 95 -
 β-Nicotinamide adenine dinucleotide phosphate, reduced tetrasodium salt (β-NADPH)
 β-NicotinaMide adenine dinucleotide 2'-phosphate reduced tetrasodiuM salt, reduced
 β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate
 β-Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Salt(Reduced Form) 〔NADPH
 β-Nicotinamide adenine dinucleotide 2'-phosphate reduced tetrasodium salt, 95%, reduced
 b-Nicotinamide-adenine dinucleotide phosphate, reduced form, tetrasodium salt - min 95%
 β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt ,99% [reduced]
 β-Nicotinamide  adenine  dinucleotide  2μ-phosphate  reduced  hydrate  tetrasodium  salt
 β-NicotinaMide adenine dinucleotide phosphate, reduced forM, tetrasodiuM salt (Reduced CoenzyMe-II)
 β-NicotinaMide Adenine Dinucleotide Phosphate TetrasodiuM Salt reduced forM [for BiocheMical Research]
 beta-NicotinaMide Adenine Dinucleotide Phosphate TetrasodiuM Salt reduced forM [for BiocheMical Research]
 Coenzyme II Tetrasodium Salt
beta-NADPH Tetrasodium Salt
TPNH Tetrasodium Salt
beta-Triphosphopyridine Nucleotide Tetrasodium Salt
 2'-(Dihydrogen Phosphate) 5'-(Trihydrogen Pyrophosphate)adenosine 5'5'-Ester 1,4-Dihydro-1-β-D-ribofuranosylnicotinaMide TetrasodiuM Salt Hydrate
 β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt,β-NADPH, 2′-NADPH, CoenzymeII reduced tetrasodium salt, Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt,
 β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate,β-NADPH, 2′-NADPH hydrate, CoenzymeII reduced tetrasodium salt, Dihydronicotinamide adenine dinucleotide phosphate te
 β-NADPH,  2μ-NADPH,  Coenzyme  II  reduced  tetrasodium  salt,  NADPH  Na4,  TPNH2  Na4,  Triphosphopyridine  nucleotide  reduced  tetrasodium  salt,  Dihydronicotinamide  adenine  dinucleotide  phosphate  tetrasodium  salt
 β-NADPH,  2μ-NADPH  hydrate,  Coenzyme  II  reduced  tetrasodium  salt,  NADPH  Na4,  TPNH2  Na4,  Triphosphopyridine  nucleotide  reduced  tetrasodium  salt,  Dihydronicotinamide  adenine  dinucleotide  phosphate  tetrasodium  salt
 |  | [EINECS(EC#)] 
 220-163-3
 |  | [Molecular Formula] 
 C21H26N7Na4O17P3
 |  | [MDL Number] 
 MFCD00036263
 |  | [MOL File] 
 2646-71-1.mol
 |  | [Molecular Weight] 
 833.35
 | 
 | Chemical Properties | Back Directory |  | [Appearance] 
 off-white to light yellow powder
 |  | [Melting point ] 
 >250°C (dec.)
 |  | [storage temp. ] 
 −20°C
 
 |  | [solubility ] 
 10 mM NaOH: soluble50mg/mL, clear
 |  | [form ] 
 Powder
 |  | [color ] 
 White to Off-white
 |  | [Water Solubility ] 
 Soluble in water (50 mg/ml).
 |  | [Sensitive ] 
 Light Sensitive
 |  | [λmax] 
 260 and 340 nm
 |  | [Merck ] 
 14,6348
 |  | [InChIKey] 
 ZQJHSLJFGRIJQN-LRANKJFRNA-N
 | 
 | Hazard Information | Back Directory |  | [Chemical Properties] 
 off-white to light yellow powder
 |  | [Uses] 
 One of the biologically active forms of nicotinic acid. Differs from NAD by an additional phosphate group at the 2’position of the adenosine moiety. Serves as a coenzyme of hydrogenases and dehydroge
nases. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions.
 |  | [Description] 
 NADPH(2646-71-1) is the reduced form of the coenzyme NADP+; used in anabolic reactions such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.
 NADPH, Tetrasodium Salt is a A ubiquitous coenzyme that acts as an electron donor in many reactions utilizing dehydrogenase and reductase enzymes. It is generated by reduction of the electron acceptor NADP+. The following biological pathways involve NADPH: formation of carbohydrate from CO2 during photosynthesis, maintenance of high levels of reduced glutathione in erythrocytes, reduction of thioredoxin.
 |  | [Mechanism of action] 
 β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).
 |  | [Reactions] 
 Nadph tetrasodium salt is one of the biologically active forms of nicotinic acid. Differs from NAD by an additional phosphate group at the 2’position of the adenosine moiety. Serves as a coenzyme of hydrogenases and dehydroge
nases. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions.
 |  | [Application] 
 NADPH is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various biological reactions. In plants, NADPH is produced by ferredoxin-NADP+ reductase in the last step of the electron chain during photosynthesis. In animals is it predominantly produced by the pentose phosphate pathway, but is also generated by key mitochondrial enzymes. NADPH provides the reducing equivalents for biosynthetic reactions and the oxidation-reduction involved in protecting against the toxicity of reactive oxygen species.It is also used for the synthesis of lipids and cholesterol and during the process of fatty acid chain elongation.
 |  | [General Description] 
 
 A ubiquitous coenzyme that acts as an electron donor in many reactions utilizing dehydrogenase and reductase enzymes. It is generated by reduction of the electron acceptor NADP+. The following biological pathways involve NADPH: formation of carbohydrate from CO2 during photosynthesis, maintenance of high levels of reduced glutathione in erythrocytes, reduction of thioredoxin. |  | [Biological Activity] 
 NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase.
 β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).
 |  | [Biochem/physiol Actions] 
 NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase.
 |  | [storage] 
 -20°C
 |  | [Purification Methods] 
 Purification is mostly similar to that of NADH above. [Beilstein 26 III/IV 3671.]
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