| Identification | More | [Name]
2'-Deoxyadenosine 5'-phosphate | [CAS]
653-63-4 | [Synonyms]
2'-DEOXYADENOSINE 5'-MONOPHOSPHATE
2-DEOXYADENOSINE-5-MONOPHOSPHATE
2'-DEOXYADENOSINE-5'-MONOPHOSPHORIC ACID
2'-DEOXYADENYLIC ACID
D-AMP
DEOXYADENOSINE-5'-MONOPHOSPHORIC ACID
2’-deoxy-5’-adenosinemonophosphate
2'-deoxyadenosine 5'-(dihydrogen phosphate)
2’-Deoxyadenosine-5’-phosphoric acid
2-DEOXYADENOSINE 5-MONOPHOSPHATE FREE*AC ID SIGMA GR
2'-Deoxy-D-adenosine-5'-monophosphatefreeacid
[5-(6-aminopurin-9-yl)-3-hydroxy-oxolan-2-yl]methoxyphosphonic acid
Deoxyadenosine monophosphate
DEOXYADENYLIC ACID
2'-Deoxyadenosine 5'-phosphate
5'-dAMP
2''-DEOXYADENOSINE 5''-MONOPHOSPHATE FREE ACID (DAMP)
2μ-Deoxyadenylic acid, dAMP
2'-Deoxy-5'-adenylic acid
2'-Deoxyadenosine monophosphate | [EINECS(EC#)]
211-503-1 | [Molecular Formula]
C10H14N5O6P | [MDL Number]
MFCD00005753 | [Molecular Weight]
331.22 | [MOL File]
653-63-4.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystalline | [Melting point ]
148 °C | [Boiling point ]
753.5±70.0 °C(Predicted) | [density ]
2.17 | [storage temp. ]
−20°C
| [solubility ]
DMSO (Slightly) | [form ]
Crystalline Powder | [pka]
1.86±0.10(Predicted) | [color ]
White | [biological source]
synthetic (organic) | [Water Solubility ]
Soluble in 1N ammonium hhydroxide (50 mg/ml) and water. | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C10H14N5O6P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1 | [InChIKey]
KHWCHTKSEGGWEX-RRKCRQDMSA-N | [SMILES]
P(OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)C[C@@H]1O)(O)(O)=O | [CAS DataBase Reference]
653-63-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [HS Code ]
29349990 |
| Hazard Information | Back Directory | [Description]
2’-Deoxyadenosine-5''-monophosphate is a derivative of the nucleic acid, AMP, in which the hydroxyl group on the 2'' carbon of the pentose has been reduced to a hydrogen atom. It has been used in the synthesis of novel photoaffinity labels for incorporation into DNA and to study adenosine-based interactions during DNA synthesis and DNA damage.1,2,3 | [Chemical Properties]
Crystalline | [Uses]
2’-Deoxyadenosine 5’Monophosphate is the first nucleotide of the phi 29 DNA. | [Definition]
ChEBI: 2'-deoxyadenosine 5'-monophosphate is a purine 2'-deoxyribonucleoside 5'-monophosphate having adenine as the nucleobase. It has a role as a fundamental metabolite. It is a purine 2'-deoxyribonucleoside 5'-monophosphate and a 2'-deoxyadenosine 5'-phosphate. It is a conjugate acid of a 2'-deoxyadenosine 5'-monophosphate(2-). | [References]
[1] M ZOFALL B B. Two novel dATP analogs for DNA photoaffinity labeling.[J]. Nucleic Acids Research, 2000, 28 21: 4382-4390. DOI: 10.1093/nar/28.21.4382
[2] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[3] V DUARTE C J B J G Muller. Insertion of dGMP and dAMP during in vitro DNA synthesis opposite an oxidized form of 7,8-dihydro-8-oxoguanine.[J]. Nucleic Acids Research, 1999, 27 2: 496-502. DOI: 10.1093/nar/27.2.496 |
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